Fig. 3. Cardiac atrial natriuretic factor (ANF) mRNA levels of Sham (empty bars) and I/R (filled bars) mice. Influence of treatment with atenolol (A), losartan, or enalapril (B). Data are expressed as mean ± SD. The number of experiments using different preparations is indicated within each bar. Mice from each group were treated with or without drug, as indicated on the abscissae. **p<0.01, ***p<0.001, ****p<0.0001, as assessed by one-factor ANOVA followed by Bonferroni's test for selected pairs.